Unlock your health's future with
Polygenic Risk Scoring
Utilize advanced AI-driven analysis of your unique DNA sequence to uncover hidden genetic predispositions. Make informed, proactive decisions for your long-term wellness.
Beyond single genes: Understanding Polygenic Risk
Most common health conditions aren't caused by a single genetic mutation, but by the combined subtle effects of millions of variations across your genome. Our Polygenic Risk Score (PRS) technology analyzes these complex patterns.
- Deep AI Processing: We utilize machine learning algorithms trained on massive genomic databases to calculate your precise risk percentiles for dozens of complex conditions.
- Actionable Insights: A genetic predisposition is not a diagnosis. By identifying your baseline risks early, our clinicians can tailor lifestyle, nutritional, and medical interventions to keep you healthy.
- Continuous Updates: As scientific understanding of the genome evolves, your digital PRS dashboard updates, giving you a lifelong companion in personalized medicine.
Key Areas of Analysis
Cardiometabolic Health
Predispositions to elevated cholesterol, hypertension, and insulin resistance.
Neurocognitive & Wellness
Genetic markers linked to vitamin absorption, stress response, and cognitive longevity.
Discover your DNA in three simple steps
Saliva Collection
We mail a simple, painless at-home DNA collection kit. Provide a saliva sample and mail it back in the prepaid secure envelope.
Lab Sequencing & AI
Our CLIA-certified partner lab extracts your DNA, evaluating 13,000+ genomic variants and calibrating against global ancestries via the PGS Catalog.
Clinical Review
Review your secure report with risk percentiles and Z-scores. Tele-consultations provide customized preventative protocols.
Polygenic Risk Score (PGRS) Clinical Results
Real computational output calculated by the PGS Catalog Calculator (pgsc_calc v2.0.0) across 2,576 reference genomes.
Higher predisposition than 71.7% of ancestry-matched individuals.
+0.62 standard deviations from reference population mean.
Calibrated against 1000 Genomes Project (681 AFR samples).
63.6% high-confidence overlap across genome sequencing.
Adjusted Score Distributions (PGS001851_hmPOS_GRCh38)
Actual output from report.html comparing patient sample (pink) against the 1000 Genomes reference cohort (cyan).
Gastroesophageal Reflux Disease & Esophagitis
"Privé F et al. Am J Hum Genet (2022). doi:10.1016/j.ajhg.2021.11.008"
The patient carries above-average genetic variants linked to esophageal tissue inflammatory response. This is not a diagnosis of disease, but a valuable clinical roadmap for preventative care.
- Alkaline and anti-inflammatory nutrition protocol.
- Targeted digestive enzyme and mucosal barrier compounds.
- Annual clinical telemetry check-in with medical provider.
Knowledge is the best medicine
Join thousands of patients taking proactive control of their health trajectory through the power of clinical-grade genetics.
Payment & Billing
Straightforward payment for every treatment
PrecisionMeDNA is a cash-pay practice across all services, which keeps your pricing clear and your care free of insurance-network restrictions. We don't bill insurance directly — but we make it easy to use the health funds you already have, and we give you everything you need to seek reimbursement on your own plan.
HSA & FSA accepted
Use your Health Savings or Flexible Spending Account toward any procedure, applied directly at the time of payment.
Cash-pay pricing
One clear price per service, paid at the time of care — no surprise network billing and no claims to chase first.
Reimbursement support
After your visit you'll receive an itemized superbill to submit to your insurer for possible out-of-network reimbursement.
The same terms apply to every service
HSA/FSA · Cash-pay · Superbill providedPlease note: PrecisionMeDNA is an out-of-network, cash-pay provider and does not submit claims to insurance carriers. A superbill is provided on request so you may seek reimbursement under your plan's out-of-network benefits. Reimbursement is determined solely by your insurer and is not guaranteed. HSA/FSA eligibility depends on your plan administrator's rules.